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The Research Centre of Chinese Herbal Resource Science and Engineering
发布时间:2014-04-05 17:32:46  点击:[]

The Research Centre of Chinese Herbal Resource Science and Engineering was founded on April, 2005, and it is from the geographical point view, localized on the new campus of Guangzhou University of Chinese Medicine in high education centre. Since 2007, the research centre has been recognized as one national key laboratory by Guangdong Province and the Ministry of Education of P.R. China. It is also titled “Key research-based laboratory of Chinese Herbal Resource Science in High Education System of Guangdong Province”, the “Germplasm-improving and Industrialization Engineering & Technology centre of Chinese Herbal Plants” by the Government of Guangdong Province and the Central government of P.R. China.

Director of the research centre: Professor Wang Yongyan, the member of Chinese Academy of Engineering, and the honorary president of China Academy of Traditional Chinese Medicine

Research areas:

1. Ecology of Chinese medicinal plants: Germplasm resources collection, evaluation, protection and conservation of authentic, endangered and rare Chinese herbal plants.

2. Gene identification and metabolic engineering of secondary metabolism in medicinal plants.

cDNA libraries construction of commonly used offcinal plants.

Cloning and characterization of functional genes involved in effective constituent biosynthetic pathways in medicinal plants.

Gene manipulation of secondary metabolic pathways in medicinal plants.

3. Breeding and selection of medicinal plants using modern biotechnology.

4. Studies of key technology involved in industrialized production of quality Chinese herbal resources.

5. Natural Product Chemistry and Medicinal Chemistry:

Extraction, isolation, structure elucidation of biologically active compounds in medicinal plants

Quality criteria and quality control methods of Chinese medicinal plants by active ingredients

Organic synthesis, structural modification and structure-activity relationship study of bioactive natural products

Team members:

Prof. CHEN Weiwen (Professor of Chinese Medicine, M.Med, PhD)

Professor Chen Weiwen obtained his master degree in Chinese medicine in 1982 from Guangzhou University of Chinese Medicine; and a PhD in cell biology in 1988 from the Xavier-Bichat Medical School, Université Paris Diderot-Paris 7, France.

Professor Chen is currently the Vice Principal of Guangzhou University of Chinese Medicine. He currently heads two research centers, the Institute of Gastroenterology and Research Centre of Chinese Herbal Resource Science and Engineering in Guangzhou University of Chinese Medicine. He is also the leader of the national and provincial key discipline of Chinese Herbal Medicine; and the leader of Chinese Herbal Medicine Resources, the key discipline of the Ministry of Education of China.

Professor Chen has served as a council member of the Chinese pharmacological society, the vice-president of the Guangdong pharmacy society, executive member of the council of Guangdong pharmacological society, committee member of the department of life sciences, National Natural Science Foundation of China.

Prof. Chen is also the editor in chief of the “Journal of Guangzhou University of Traditional Chinese Medicine”, member of the editorial board of “Traditional Chinese Drug Research and Clinical Pharmacology” and “New Journal of Traditional Chinese Medicine”.

Prof. Chen is accomplished in application of integrated traditional Chinese and western medicine on gastric-intestinal diseases, pharmacology and the sustainable and comprehensive utilization of Chinese herbal resources. His research interests focus firstly on curing gastric-intestinal diseases using integrated traditional Chinese and western medicine, secondly on novel drugs R & D.

Selected Publications

1. Chen Wei-wen, Wang Ying-fang, Lao Shao-xian, et al. Profile of gene differential expression in chronic gastritis with deficiency of spleen-QI patients. Chinese Journal of Pathophysiology. 2008,24(1):148-152

2.Wang Ying-fang, Chen Wei-wen, Lao Shao-xian, et al. Comparison of differentially expressed gene between deficiency of spleen-QI syndrome and splenogastric hygropyrexia syndrome pqtients with chronic gastritis. Chinese Journal of Pathophysiology. 2008,24(2):320-324

3.Chen Yu-long, Chen Wei-wen, Wang Ying-fang, et al. Bioinformatics Research of Gene Arrays in Splenasthenic Syndrome of Chronic Superficial Gastritis Patients. Chinese Journal of Integrative Medicine.2009

4.Zhang Zili,Chen Weiwen. Effects of extracts from Codonopsis pilosula,Astragalus membranaceus,Atractylodes macrocephala and Glycyrrhiza uralensis on intestinal crypt cells proliferatio. Chinese medicine and clinical pharmacology. 2002; 18(1):10-12

5.Zhang Zili,Chen Weiwen. Huangqi and atractylodes extracts on intestinal epithelial cell migration. Chinese herbal medicine . 2002;33(10):912-915

6.Chen Weiwen,Zhang Zili,Wang Jianhua,Shen Xiaoling,Han Ling,Zhou Lian,Xu Qin. Effects of Extracts from Codonopsis Pilosula, Atractylodes Macrocephala and Their Combination on Intestinal Epithelial Cell Migration and Proliferation. Chinese Pharmacological Bulletin. 2002;18(4):444-447

7.Zhang Zili, Chen Weiwen. Effect of Astragalus Injection in Promoting IEC-6 Cell Differentiation through Activating Ornithine Decarboxylas. Chinese Journal of Integrated Traditional and Western Medicine. 2002;22(6):439-443

8.Zhang Zili,Chen Weiwen. Plating densities, alpha-difluoromethyl- ornithine effects and time dependence on the proliferation of IEC-6 cells. Chinese Medical Journal. 2002;115(4):518-520

9.Wang Zhou,Chen Weiwen,Li Ruliu,Sun Jingbo,Wen Bin. Effect of gastrin on differentiation of rat intestinal epithelial cells in vitro. World Journal of Gastroenterology 2003;9(8):1786-1790

10.Chen Wei-wen, Li Ru-liu, Xu Qin, et al. Influence of Lian-dai Tablet on rat gastric cancer and the expression of proteins p21ras,c-erbB2,Rb and p53. Chinese Journal of Integrative Medicine. 1998, 18:252-254

11.Tan Yu-hui, Chen Wei-wen, Wu Ying-ya, et al. Efects of berberine,evodiamine and indirubin on gastric cancer cells. World Chinese Journal of Digestology. 2005;13(4):472-476

12.Tan Yu-hui, Chen Guan-lin, Guo Shu-jie, Li Yan-hong, Chen Wei-wen. Effects of berberine on growth inhibiting and apoptosis of human gastric carcinoma cells BGC-803. Chinese Pharmacological Bulletin. 2001;17(1):40-43

13.Chang Jinrong ,Wen Bin ,Wang Rujun ,Chen Weiwen , Wang Jianhua. Efects of evodiamine and berberine hydrochloride on cell apoptosis and expression of hTERT-mRNA Of hum an colorectal cancer cell line HT29. Pharmacology and clinics of Chinese materia medica. 2008,24(2):6-8

14.Chuang Jin-rong, Wen Bin, Wang Ru-jun, Chen Wei-wen, Wang Jian-hua. Effects of evodiamine and berberine hydrochloride on growth inhibiting and apoptosis of HT29 cells. Traditional Chinese Drug research and clinical pharmacology. 2008,19(3):191-194

Dr. XU Hui (Senior Research fellow of Chinese Medicine, BS, MS, PhD)

Dr. Xu Hui obtained her Bachelor of Science degree in Chemistry in 1992 and the Master of Science degree in Analytical Chemistry in 1995, respectively, from Sun Yet-sen University, P.R. China. She further made her PhD in Pharmaceutical Biology in Universitaet Tuebingen, Germany, and achieved the degree in 2004. The doctoral thesis Titled “Molecular biological and biochemical investigation of the biosynthesis of aminocoumarin antibiotics” was supervised by Prof. Lutz Heide and Prof. Shu-Ming Li.

Current Research Interests

1.Molecular genetic investigation of the biosynthesis of secondary metabolites in microorganisms: gene cloning, functional identification, gene expression, metabolic regulation.

2.Quality control of Chinese Medicine.

Selected Publications

1. Huang, H-R.; Chen, W-W.; Xu, H. Inhibitory effect of Chinese herbal medicine and related active components against Helicobacter pylori: progress and prospects. Zhong yao xin yao yu ling chuang yao li. 2008, 19(6), 508-511 (Chinese)

2. Xu, H.; Heide, L.; Li, S.-M. New aminocoumarin antibiotics formed by a combined mutational and chemoenzymatic approach, utilizing the carbamoyltransferase NovN. Chem. Biol. 2004,11, 655-662

3. Freel Meyers, C.L.; Oberthür, M.; Xu, H.; Heide, L.; Kahne, D.; and Walsh, C.T. Completion of novobiocin biosynthesis via sequential tailoring of the noviosyl ring. Angew. Chem Eng. Int. 2004, 43:67-70

4. Xu, H.; Kahlich, R.; Kammerer, B.; Heide, L.; and Li, S.-M. CloN2, a novel acyltransferase involved in the attachment of the pyrrole-2-carboxyl moiety to the deoxysugar of clorobiocin. Microbiology 2003, 149, 2183-2191

5. Xu, H.; Wang, Z.-X.; Schmidt, J.; Heide, L.; and Li, S.-M. Genetic analysis of the biosynthesis of the pyrrole and carbamoyl moieties of coumermycin A(1) and novobiocin. Mol. Genet. Genomics 2002, 268, 387-396

6. Xu, H.; Lai, R.-J. Determination of Vitexin in Cajanus cajan (L.) Millsp. Zhong yao cai. 1998, 21(9), 461(Chinese)

7. Xu, H.; Zeng, Y.-E., Zhong, J.-J. TLC Determination of Ginsenoside Rg1 in Ginseng and its Preparations. Zhong yao xin yao yu ling chuang yao li. 1998, 9(2), 106-107 (Chinese)

Dr. HE Rui (Associate Research Fellow, BS, MS, PhD.)

Dr. He Rui received her Bachelor degree and Master degree in 1993 and 1996, respectively, from Guangzhou University of Chinese Medicine, P.R. China. After working as a teaching assistant and lecturer in Phytochemistry of Chinese herbal medicine for 5 years, she went to the University of Manchester, UK as a visiting scientist and was successful in the ORS (Overseas Research Studentship) application for a PhD opportunity in 2002. The doctoral research was involved in molecular mechanism of Programmed Cell Death in plants. She achieved her PhD in Plant Sciences in 2006 from the University of Manchester, UK. Her current research interest focus on studying medicinal plants using modern biological and analytic techniques:

1. Sustainable development and utilization of medicinal plants (Gene manipulation, breeding, GAP, establishment of grading standards, etc.).

2. Secondary metabolites of medicinal plants.

Publications and Presentations

1. Rui He, Georgina E. Drury, et., al. Metacaspase-8 Modulates Programmed Cell Death Induced by Ultraviolet Light and H2O2 in Arabidopsis. Journal of Biological Chemistry, 2008, 283(2):774-783.

2. Vitalie I. Rotari, Rui He and Patrick Gallois. Death by proteases in plants: whodunit, Physiologia Plantarum, 2005, 123: 376-385.

3. HE R, ROTARI VI, BONNEAU L and GALLOIS P. Caspase-like activities and Programmed Cell Death induced by UV in Arabidopsis. In "Cell Biology and Instrumentation: UV Radiation, Nitric Oxide and Cell Death in Plants." Ed.Ya. Blume, D. Durzan, P. Smertenko, NATO mono graphy IOS Press, 2006.

4. R. He, V. Rotari, M. Willer and P. Gallois, Are Plant Metacaspases Functional Homologues of Animal Caspases? Annual Conference of Society of Experimental Biology, Barcelona, Spain, July, 2005.

5. Dian Chen, Rui He, Studies of active constituents with analgesic and antemetic actions from Rhizoma Alpiniae Officinarum. Journal of Guangzhou University of Traditional Chinese Medicine. 2001, 18(3): 240-242

6. Rui He, Tao Wang, Research progress of the natural chemical component Galangin. LiShizhen Medicine and Materia Medica Research. 1999, 10(10): 788-789

7. Rui He, Dian Chen, Quantitative analysis of taxol in Taxus chinensis var. mairei produced in Lechang. Journal of Chinese Medicinal Materials. 1999, 22(8):388-388

Dr. LIU Jiawei (Dr, BS, MMedEng, PhD)

Dr. Liu Jiawei obtained his Bachelor of Pharmacology in 1998 from Nanjing University of Chinese Medicine, Nanjing, China. After having obtained the degree of Master INGENIERIES POUR LA SANTE ET LE MEDICAMENT from University of Joseph Fourier Grenoble in 2004, He entered the Dr. LUU Bang’s Laboratory of Organic Chemistry of Natural Substances in order to work towards to the PhD degree at University of Louis Pasteur Strasbourg. His doctoral thesis titled “Inducteurs de différenciation des cellules souches neurales: études phytochimique et pharmacologique” was under the direction of Dr. Bang LUU and Prof. Michel Rohmer. Having obtained his PhD in CHIMIE ORGANIQUE BIOLOGIQUE in October of 2007, He then worked as a postdoctoral fellowship and spent a year in the laboratory of Dr. Francoise Gueritte at Institut de Chimie des Substances Naturelles -Centre National de la Recherche Scientifique (ICSN-CNRS), Campus Gif-sur-Yvette, where he identified a novel class of acetylcholinesterase inhibitors from plant extracts and prepared for some analogues of these bioactive benzofuran derivatives to study the structure-activity relationship.

Current Research Interests

1. Natural Products Chemistry: Bioassay-guided isolation, screening and structural identification of biologically active compounds from plants, marine organisms and Chinese Medicine.

2. Medicinal Chemistry: Organic synthesis, structural modification and structure-activity relationship study of bioactive natural products.

3. Chemogenomics and Pharmacogenomics:

(1) Chemical screening for small molecules that can regulate asymmetric division and differentiation of stem cells.

(2) Exploring the gene expression patterns and biomacromolecules components of asymmetric stem cell division with small molecules

Selected Publications

1. TRACQUI P., LIU J., COLLIN O., CLEMENT-LACROIX J., PLANUS E. Global Analysis of Endothelial Cell Line Proliferation Patterns based on Nutrient-depletion Models: Implications for a Standardization of Cell Proliferation Assays. Cell Proliferation. (2005). 38 (3): 119 -135.

2. LIU J.*, TABOPDA T.*, NGADJUI B., LUU B. Cytotoxic Triterpene and Sesquiterpene Lactones from Elephantopus mollis and Induction of Apoptosis in Neuroblastoma Cells. Planta Medica. (2007). 73: 376-380. (*equal contribution)

3. LIU J., TIAN S., DE BARRY J. LUU B. Panaxadiol Glycosides that Induce Neuronal Differentiation in Neurosphere Stem Cells. Journal of Natural Products. (2007). 70 (8): 1329-1334.

4. HAUSS F., LIU J., MICHELUCCI A., COOWAR D., HEUSCHLING P., and LUU B. Dual Bioactivities of a New Class of Compounds: On Differentiation of Neural Stem Cells and Modulation of Neuro-Inflammation. Bioorganic & Medicinal Chemistry Letters. (2007). 17(15): 4218-4211.

5. TABOPDA T., NGOUPAYO J., LIU J., SHAIQ ALI M., KHAN S.N., NGADJUI B., LUU B. Further Cytotoxic Sesquiterpene Lactone from Elephantopus mollis Kunth. Chemical & pharmaceutical bulletin. (2008). 56 (2): 231-233.

6. TABOPA T., NGOUPAYO J., LIU J., SHAIQ ALI M., NGADJUI B., LUU B. Alpha-Glucosidase Inhibitors Ellagic Acid Derivatives with Immunoinhibitory Properties from Terminalia superba. Chemical & pharmaceutical bulletin. (2008). 56 (6): 847-850.

7. TABOPDA T., NGOUPAYO J., LIU J., MITAINE-OFFER A.C., KHAN S. A., SHAIQ ALI M., NGADJUI B., LACAILLE-DUBOISs M.A., and LUU B. Bioactive Aristolactams from Piper umbellatum. Phytochemistry. (2008). 69 (8):1726-1731.

Mr. ZHAN Ruoting (Associate Professor of Chinese Medicine, B.S., M.S.)

Mr. Zhan Ruoting obtained his Bachelor of Science and Master of Science degrees in 1992 and 2003, respectively, from Guangzhou University of Chinese Medicine, Guangzhou, P.R. China. He is currently the vice-director of Research Center of Chinese Medicine Resources Science and Engineering, Guangzhou University of Chinese Medicine.

Mr. Zhan specializes in studying resources of Chinese medicinal materials. His researches focus on authenticating the medicinal herbs in South China area, which includes resources survey on the botanical origins, identification of the commercial products, the pharmacognosy studies on different species, etc. His most recent work emphasizes the importance of the sustainable development and utilization of traditional Chinese medicine resources. He and his colleagues are devoted to the studies on standardization cultivation of herbal plants used in Chinese medicine and the constructions on demonstrative bases of GAP (Good Agricultural Practice).

Selected Publications:

1. Deng Wen, Xia Quan, Zhan Ruoting, Cheng Jin-le, Xu Xiao-feng. Comparison of Notoginsenoside R1 and Ginsenoside Rg1 and Rb1 of Different Powder from Panax notoginseng. Research and Practice of Chinese Medicines. (2007). 21(6):50-53.

2. Deng Wen, Xia Quan, Zhan Ruoting, Cheng Jin-le. Research Progress on Ultra-fine Pulverization Technology in Traditional Chinese Medicine. Food and Drug. (2007). 9(11A):59-62.

3. Zhan Ruo-ting, Huang Hai-bo, Pan Chao-mei, Xu Hong-hua, Chen Wei-wen. Morphological Comparison of Different Cultured Varieties of Rhizoma Alpiniae Officinarum in GAP Base. Research and Practice of Chinese Medicines. (2007). 21(2):3-6.

4. Zhan Ruoting, Ding Ping, Pan Chaomei, Xu Honghua, Chen Weiwen and Guo Jianping. Morphological Comparison of Different Cultured Variety of Radix Morindae Officinalis in GAP Base. Journal of Guangzhou University of Traditional Chinese Medicine. (2003). 20(1):72-75.

5. Pan Chaomei, Zhan Ruoting, Ding Ping and Xu Honghua. Effects of Various Organic Fertilzers on Growth and Mineral Nutrient Absorption of Morindar officinalis. Jorunal of Chinese Medicinal Materials. (2002). 25(10):699-700.

6. Zhan Ruoting, Pan Chaomei, Huang Haibo. Application on the field work of Pharmaceutical Botany. Pharmaceutical Education. (2002). 18(3):45.

7. Pan Chaomei, Huang Haibo, Zhan Ruoting, and Xu Honghua. Diagnosis and Integrative Evaluation on Soil Fertility of Three Chinese Medicinal Materials in GAP Plots. Jorunal of Chinese Medicinal Materials. (2002). 25(3):157-159.

8. Zhan Ruoting, Zeng Huifang, Liang Yongshu, Feng Qianru, Cheng Yunping and Lin Yiping. Botanical Origin Investigation and Pharmacognosis Identification of Radix Atalantiae Buxifoliae. Journal of Guangzhou University of Traditional Chinese Medicine. (2000). 17(2): 170-172.

9. Tan Shuhui, Zhan Ruoting. Handbook of the herbal medicine identification on the field work. Science and Technology Press of Guangdong Province, 2003

Dr. YANG Jinfen (Associate Research Fellow, BS, PhD.)

Dr. Yang Jinfen received her Bachelor degree in Biotechnology in 2001and her PhD in Plant Molecular Biology in 2006, respectively, from South China Agricultural University, Guangzhou, P.R. China. She then worked as a postdoctoral research scientist in Guangzhou University of Chinese Medicine, P.R. China from 2006-2008, under the supervision of Prof. Wang Yongyan and Prof. Chen Weiwen. She is now appointed as Associate Research Fellow in the university. Her research focus on following areas:

1. Genetic engineering of plant about anti-stress;

2. Protection, development and utilization of traditional Chinese medicine;

3. Normal and molecular breeding of Amomum villosum.

Selected publications:

1. Jinfen Yang, Zhenfei Guo. Cloning of a 9-cis-epoxycarotenoid Dioxygenase Gene (SgNCED1) from Stylosanthes guianensis and its Expression in Response to Abiotic Stresses. Plant Cell Report, 2007, 26:1383–1390.

2. Yiming Zhang, Jinfen Yang, Shaoyun Lu, et al. Overexpressing SgNCED1 in tobacco increases ABA level, antioxidant enzyme Activities, and stress tolerance. Journal of Plant Growth Regulation, 2008, 27:151–158.

3. Qin C, Lu S, Yang J, Han L. Tissue culture and plantlet regeneration of manilagrass. International Turfgrass Society Research Journal, 2005, 10: 555-557.

4. Yang Jin-fen, Guo Zhen-fei, Yang Jing. Cloning and characteristics of 9-cis-epoxycarotenoid dioxygenase gene (SgNCED1) from Stylosanthes guianensis. Acta Prataculturae Sinica. (2007). 16(3):21-28.

Dr. YAN Ping (Postdoctoral Research Scientist. BEng, MEng, EngD)

Dr. Yan Ping obtained her Bachelor degree and Master degree of Fermentation Engineering in 1999 and 2004, respectively, from Guangxi University. She went to South China University of Technology for an EngD program, worked on DNA Fingerprint Construction of Fallopia Multiflora. She got her doctoral of Engineering in 2007.

Her current research interest focus on studying medicinal plants using modern biological and analytic techniques:

a) Secondary metabolites of medicinal plants and Quality standards for Chinese medicine research

b) Chinese Herbal biotechnology and DNA molecular markers to identify Chinese herbal medicine research

Selected publications:

1. Yan P, Pang QH, Jiao XW, Zhao X, Shen YJ, Zhao SJ. Genetic variation and identification of cultivated Fallopia multiflora and its wild relatives by using chloroplast matK and 18S rRNA gene sequences [J]. Planta Medica, 2008, 74 (12):1504-9.

2. Yan Ping,Jiao Xu-wen,Pang Qi-hua,Zhao Shu-jin.Analysis of 18S rRNA Gene Sequence of Polygonum multiflorum [J].Journal of South China University of Techenology(Natural Science Edition) , 2008,36(4):151-4.

3. Yan Ping,Zhao Shu-jin.Genomic DNA Extraction from the Polygonum multiflorum Thunb [J].Lishizhen Medicine and Materia Medica Research, 2007, 18(3):607-9.

4. Yan Ping,Guo Jie-wen ,Jiao Xu-wen,Pang Qi-hua,Zhao Xuan, Zhao Shu-jin. Establishment of Polymorphism Reaction for Amplified Fragment Length and Silver-staining System for Polygonum multiflorum Thunb [J].Herald of Medicine, 2008, 27(7):757-60.

5. Yan Ping,Jiao Xu-wen,Pang Qi-hua,Zhao Shu-jin. Study on the Genetic Variation of Polygonum multiflorum Thunb species by sequences analysis of chloroplast matK gene [J]. Modern Food Science and Technology,2007,23(8):9-13.

6. Yan Ping, Zhao Shu-jin. Transgenic technology in plant antibody applications [J].Chemistry of Life, 2006, 26(1):20-2.

7. Shen Yan-jing, Yan Ping,Zhao Xuan, Pang Qi-hua,Zhao Shu-jin. Application of ISSR Marker and Its Sequence to Investigation of Genetic Bariation of Aquilaria sinensis [J]. Journal of South China University of Techenology(Natural Science Edition) ,2008,36 (12):128-32.

8. ZHAO Zhen-hua, YAN Ping, JIAO Xu-wen, ZHAO Shu-jin. Establishment and Optimization of ISSR-PCR Reaction System for Polygonum multiflorum Thunb. [J]. Lishizhen Medicine and Materia Medica Research,2008,(3):568-9.

9. Pang Qi-hua,Yan Ping,Zhao Xuan, Zhao Shu-jin. Extraction of Genomic DNA from Ainia officinarum Hance [J]. Lishizhen Medicine and Materia Medica Research, 2008, 19(5):1187-9.

10. JIAO Xu-wen, SHEN Yan-jing, YAN Ping, ZHAO Shu-jin. Comparative Karyological Study on three Cultured Variveties of Polygonum multiflorum [J]. Journal of Chinese Medicinal Materials,2006,29(12):1273-6.

11. TAN Xue-mei,SHEN Yan-jing, YAN Ping, ZHENG Chuan-jin, ZHAO Shu-jin. Construction and analysis of Polygonum multiflorum cDNA library [J]. Chinese Traditional and Herbal Drugs, 2008, 39 (11): 1716-20.

12. TAN Xue-Mei, SHEN Yan-Jing, YAN Ping, ZHAO Shu-Jin. Comparison and Improvement of Methods for Total RNA Isolation from Polygonum multiflorum Thunb[J]. Letters in Biotechnology,2008,(3):414-6.

13. JIAO Xu-wen, ZHANG Xiang-nian, ZHAO Xuan, YAN Ping, ZHAO Shu-jin. Comparison of Content of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside and Anthraquinon in Different Ploidy Radix Polygoni Multiflori. Journal of Chinese Medicinal Materials, 2007, 30(12):1487- 9

Research Projects Accomplished &Underway by Our Team

1. Germplasm standardized reorganization and preservation of Lonicera confusa DC. and Morinda officinalis How var. officinalis (PI). (2005.03-2007.12)

Funded by: China Ministry of Science and Technology.

2. Resources investigation of endangered medicinal plant Morinda officinalis How var. officinalis (PI). (2008.09-2009.06)

Funded by: China Ministry of Science and Technology.

3. Fine variety breeding and expanded production of Amomum villosum Lour. (PI). (2007.10-2009.10)

Funded by National Development & Reform Commision of China.

4. Re-development of Wei Nai An Capsules-a famous high quality brand Chinese patent medicine of Guangdong for chronic gastrointestinal diseases (PI). (2008.01-2010.12) (Co-operation project with ZhongYi Pharmaceutical Company Ltd.)(A breakthroughs in key areas of Hong Kong Guangdong Cooperation projects.)

Funded by: People’s government of Guangdong province and Government of Hong Kong Special Administrative Region (HKSAR).

5. Characterization of genes involved in organ size from an endangered medicinal plant Nervilia fordii(Hance)Schltr. (PI). (2009.01-2010.01)

Funded by: Ministry of Education, P.R. China.

6. Germplasm bank of medicinal plants in South China area (PI). (2003.12-2007.08)

Funded by: People’s government of Guangdong province and People’s government of Guangzhou.

7. A quality control system setting up for medicinal plant in South China area based on TGA standard from Australia (PI). (2009.01-2011.12)

Funded by: People’s government of Guangdong province, P.R.China.

8. Characterization of genes involved in branching from medicinal plant Nervilia fordii(Hance)Schltr. (PI). (2008.01-2010.01)

Funded by: National Natural Science Foundation of P. R. China.

9. Germplasm-improving engineering of Chinese Herbal Plant Amomum villosum-A sub-program of the National Science and Technology Infrastructure Program in the 11th Five-year Plan period. (PI). (2006.10-2009.09)

Funded by: The Ministry of Science and Technology of P.R.China.

10. HPLC Fingerprints of Panax quinquefolium L, Astragalus membranaceus (Fisch.) Bunge and Panax Notoginseng. (Cooperation with ZEUS medicine group, Zhongshan, P.R.China.) (2009.4-2010.4)

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